Uric Acid Nephrolithiasis: A Systemic Metabolic Disorder
نویسندگان
چکیده
منابع مشابه
Uric Acid Nephrolithiasis: A Systemic Metabolic Disorder.
Uric acid nephrolithiasis is characteristically a manifestation of a systemic metabolic disorder. It has a prevalence of about 10% among all stone formers, the third most common type of kidney stone in the industrialized world. Uric acid stones form primarily due to an unduly acid urine; less deciding factors are hyperuricosuria and a low urine volume. The vast majority of uric acid stone forme...
متن کاملMetabolic syndrome and uric acid nephrolithiasis.
The metabolic syndrome describes a cluster of metabolic features that increases the risk for type 2 diabetes mellitus and cardiovascular disease. The prevalence of uric acid nephrolithiasis is higher among stone-forming patients with features of the metabolic syndrome such as obesity and/or type 2 diabetes mellitus. The major determinant in the development of idiopathic uric acid stones is an a...
متن کاملTheobromine Inhibits Uric Acid Crystallization. A Potential Application in the Treatment of Uric Acid Nephrolithiasis
PURPOSE To assess the capacity of methylxanthines (caffeine, theophylline, theobromine and paraxanthine) to inhibit uric acid crystallization, and to evaluate their potential application in the treatment of uric acid nephrolithiasis. MATERIALS AND METHODS The ability of methylxathines to inhibit uric acid nucleation was assayed turbidimetrically. Crystal morphology and its modification due to...
متن کاملBilateral uric acid nephrolithiasis and ureteral hypertrophy in a free-ranging river otter (Lontra canadensis).
We report the first case of uric acid nephrolithiasis in a free-ranging river otter (Lontra canadensis). A 7 yr old male river otter collected from the Skagit River of western Washington (USA) had bilateral nephrolithiasis and severely enlarged ureters (one of 305 examined [0.33%]). The uroliths were 97% uric acid and 3% protein. Microscopic changes in the kidney were confined to expansion of r...
متن کاملMetabolic syndrome and nephrolithiasis
PROBLEM This review focuses on the association between the metabolic syndrome (MS) and nephrolithiasis. FINDINGS Associations between nephrolithiasis and systemic diseases are recognized, including atherosclerosis, cardiovascular (CV) disease, hypertension (HNT), diabetes mellitus (DM)-composite risk factors grouped as the MS. Kidney stones incidence is increasing in this particularly high ri...
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ژورنال
عنوان ژورنال: Clinical Reviews in Bone and Mineral Metabolism
سال: 2011
ISSN: 1534-8644,1559-0119
DOI: 10.1007/s12018-011-9106-6